Anastrozole (Anaridex 1 mg) 1 mg tablet is a non-steroidal aromatase inhibitor (AI), used to decrease circulating estrogen levels in the treatment of estrogen-responsive breast cancer in postmenopausal women.
Drug =Anastrozole
Number of Pills Per Product = 10
Strength = 1 mg
Manufacturer = Healing Pharma
How To Take
This medicine may be taken with or without food. Try to take it at the same time each day.
Anastrozole must be taken regularly for it to be effective. Continue taking this medicine even when you feel better.
Take Anastrozole precisely as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Dosage of Anastrozole (Anaridex 1 mg) 1 mg
When Anastrozole is used as adjuvant therapy for postmenopausal women with hormone receptor-positive early breast cancer, breast cancer in postmenopausal women, as monotherapy in hormone receptor-positive advanced cases or patients with disease progression following tamoxifen therapy: 1 mg once a day, treatment may be continued up to 5 years for adjuvant therapy or until tumor progression for advanced breast cancer.
Missed Dose
If you miss a dose, skip the missed dose and return to your regular dosing schedule. If you often forget to take your medicine, let your doctor and pharmacist know.
Do not double a dose under any circumstances.
Overdose of Anastrozole (Anaridex 1 mg) 1 mg
If you think you may have used Anastrozole more than the usual dose, please seek medical help immediately.
Contraindications
People with the following medical conditions should not take Anastrozole:
- Monotherapy in pre-menopausal women with breast cancer
- Severe renal impairment (CrCl <20 mL/min)
- Pregnancy and lactation
Side Effects
Anastrozole may have the following side effects:
- Decreased bone mineral density (e.g., osteoporosis)
- Hypercholesterolemia
- Hypersensitivity reactions (e.g., anaphylaxis, angioedema, urticaria)
- Ischemic heart disease
- Lymphedema
- Angina pectoris
- Dyspnea
- Chest pain
- Cataract
- Gastrointestinal distress
- Anorexia
- Nausea
- Vomiting
- Constipation
- Diarrhea
- Abdominal pain
- Dyspepsia
- Gastrointestinal disease
- Xerostomia
- Fatigue
- Pain
- Weakness
- Bone fracture
- Accidental injury
- Weight gain
- Arthritis
- Myalgia
- Arthralgia
- Back pain
- Ostealgia
- Headache
- Dizziness
- Paresthesia
- Carpal tunnel syndrome
- Mood disorder
- Depression
- Insomnia
- Anxiety
- UTI
- Pelvic pain
- Mastalgia
- Vulvovaginitis
- Vaginal dryness or bleeding
- Pharyngitis
- Cough
- Flu-like symptoms
- Sinusitis
- Rash
- Vasodilation
- Hypertension
- Hot flushes
Warnings
Do not use Anastrazole in people with the following conditions:
- Breast cancer during pre-menopausal years (have menstrual periods whether regular or irregular and are considered to be in your reproductive years)
- Severe kidney disease
- Pregnancy
- Lactation
Inform your doctor and pharmacist if you are taking or using any of these medicines:
- Estrogen
- Tamoxifen
Inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and non-prescription medicines.
This list does not include all medicines that may interact with Anastrozole.
How Does Anastrozole (Anaridex 1 mg) 1 mg Work?
Anastrozole exerts its anti-estrogenic effects by selectively and competitively inhibiting the aromatase enzyme, responsible for converting androstenedione to estrone and testosterone to estradiol, thereby resulting to decreased serum estradiol concentration and decreased tumor mass, thus slow down the progression in patients with tumors responsive to hormones.
Uses
Anastrozole is used to treat the following conditions:
- Adjuvant therapy for postmenopausal women with hormone receptor-positive early breast cancer
- Breast cancer in postmenopausal women.
Special Precautions and Connected Warnings
Take special precautions if you have the following conditions:
- Hyperlipidemia
- Pre-existing osteopenia
- Ischemic cardiac disease
- Moderate to severe hepatic impairment
- Mild to moderate renal impairment
- Avoid alcohol
Storage Conditions
- Store between 20-25°C. This is a cytotoxic drug. Follow applicable procedures for receiving, handling, administration, and disposal.
- As this is a cancer medicine, always return any unused or expired tablets to the clinic, hospital, or pharmacy for disposal. Do not throw it away in the household waste.
- Store in a cool, dry place away from the reach of children.
- Do not use Anastrozole that is expired or out of date.
