Calcitriol (Rocaltop 0.25) 0.25 mg capsule is the most potent metabolite of vitamin D that plays an important role in the regulation of plasma calcium with parathyroid hormone (PTH) by enhancing the absorption of dietary calcium and phosphate from the gastrointestinal tract, thereby promoting renal tubular reabsorption of calcium in the kidneys, thus stimulating the release of calcium stores from the skeletal system.
Drug =Calcitriol
Number of Pills Per Order = 10
Strength = 0.25 mg
Manufacturer = Healing Pharma
How To Take
This medicine may be taken with or without food. If this medicine is causing stomach discomfort, take it with food or immediately after meals. Try to take it at the same time each day.
Calcitriol must be taken regularly for it to be effective. Continue taking this medicine even when you feel better.
Take this medicine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Dosage of Calcitriol (Rocaltop 0.25) 0.25 mg
Adult: Hypocalcemia: Initial: 0.25 mcg daily. Dose reduction, dosing interruption, or discontinuation may be required according to serum Ca levels, tolerability, and individual safety (refer to detailed product guidelines).
Postmenopausal osteoporosis: 0.25 mcg twice a day.
Missed Dose
If you miss a dose, skip the missed dose and return to your regular dosing schedule. If you often forget to take your medicine, let your doctor and pharmacist know.
Do not double a dose under any circumstances.
Overdose of Calcitriol (Rocaltop 0.25) 0.25 mg
Signs of overdose may include the following:
- Hypercalcemia
- Hypercalciuria
- Hyperphosphatemia
Seek medical help immediately.
Contraindications
People with the following medical conditions should not take Calcitriol:
- Hypercalcemia
- Metastatic calcification
- Vitamin D toxicity
Side Effects
Calcitriol may have the following side effects:
- Hypercalcemia
- Hypercalciuria
- Dry mouth
- Nausea
- Vomiting
- Constipation
- Abdominal pain
- Pancreatitis
- Weakness
- Hyperthermia
- Increased liver function tests
- Increased BUN
- Hypercholesterolemia
- Dehydration
- Anorexia
- Weight loss
- Polydipsia
- Muscle and bone pain
- Ectopic calcification
- Headache
- Somnolence
- Sensory disturbance
- Photophobia
- Apathy
- Decreased libido
- Albuminuria
- Polyuria
- Nocturia
- Nephrocalcinosis
- Rhinorrhea
- Pruritus
- Hypertension
Warnings
Do not use Calcitriol in people with the following conditions:
- High level of calcium in your blood
- Abnormal calcium deposits in tissues
- High level of vitamin D in your body
Inform your doctor and pharmacist if you are taking any of these medicines:
- Other medicines containing vitamin D
- Antacids
- Thiazide diuretics
- Digoxin
- Colestyramine
- Sevelamer
- Phenytoin
- Phenobarbital
- Corticosteroids
Inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and nonprescription medicines.
This list does not include all medicines that may interact with Calcitriol.
How Does Calcitriol (Rocaltop 0.25) 0.25 mg Work?
Calcitriol is the active form of vitamin D3, cholecalciferol, that acts by stimulating the vitamin D receptor to promote calcium absorption and transport, thus increasing serum calcium levels. It also stimulates bone resorption and renal tubular reabsorption of calcium, thereby decreasing the parathyroid hormone (PTH) and maintaining calcium-phosphate homeostasis.
Uses
Calcitriol is used to treat the following conditions:
- Hypocalcemia
- Postmenopausal osteoporosis
- Plaque psoriasis
Special Precautions and Connected Warnings
Take special precautions if you have the following conditions:
- Malabsorption syndrome
- Renal impairment
- Pregnancy and lactation
- Avoid excessive vitamin D intake and maintain an adequate dietary calcium intake
- Avoid alcohol
- It is important that you have enough calcium in your body. It may be helpful to discuss your diet plan with your doctor or dietitian.
Storage Conditions
- Store between 20-25°C. Protect from light.
- Store in a cool, dry place away from the reach of children.
- Do not use calcitriol that is expired or out of date.
