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Cronotol 250 | Disulfiram 250mg – 10 Tablets

$1.69

Disulfiram (Cronotol 250) 250 mg tablet is an aid used in the management of alcohol dependence. Once discontinued, it helps to establish self-motivation in maintaining abstinence from alcohol.

 

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Form Tabs
Usage/Application 10 Tabs
Brand Name Cronotol 250
Type Of Medicines Anti Alcoholic
Brand Healing Pharma India Pvt. Ltd.
Country of Origin Made in India

Disulfiram (Cronotol 250) 250 mg tablet is an aid used in the management of alcohol dependence. Once discontinued, it helps to establish self-motivation in maintaining abstinence from alcohol.

Drug = Disulfiram

Number of Pills Per Order = 10

Strength = 250 mg

Manufacturer = Healing Pharma

 

How To Take

This medicine may be taken with or without food.

Do not take Disulfiram if you have consumed alcohol in the last 12 hours.

Take Disulfiram precisely as directed by your doctor or according to the instructions on the label. Do not take more than instructed by your doctor.

Dosage

Adult: 800 mg as a single dose on the 1st day, reduced by 200 mg/day. Maintenance: 100-200 mg/day.

Missed Dose

If you miss a dose, skip the missed dose and return to your regular dosing schedule. If you often forget to take your medicine, let your doctor and pharmacist know.

Do not double a dose under any circumstances.

Overdose 

Signs of overdose may include the following:

  • Nausea
  • Vomiting
  • Abdominal pain
  • Diarrhea
  • Drowsiness
  • Delirium
  • Hallucinations
  • Lethargy
  • Tachycardia
  • Tachypnoea
  • Hyperthermia
  • Hypotension
  • Hypotonia
  • Hyperglycemia
  • Leukocytosis
  • Ketosis
  • Methaemoglobinemia
  • Cardiovascularcollapse
  • Coma and convulsions in severe cases

Contraindications

People with the following medical conditions should not take Disulfiram:

  • Heart failure
  • Coronary artery disease
  • History of stroke
  • Hypertension
  • Psychosis or severe personality disorders
  • Patients receiving metronidazole, paraldehyde, alcohol or alcohol-containing preparations (e.g., cough syrups, tonics) or alcohol-based topical preparations

Seek medical help immediately.

Side Effects

Disulfiram may have the following side effects:

  • Drowsiness
  • Fatigue
  • Garlic-like or metallic aftertaste
  • Stomachupsets
  • Body odor
  • Halitosis
  • Headache
  • Impotence
  • Acneiform or allergic dermatitis
  • Peripheral and optic neuropathies
  • Psychotic reactions
  • Disulfiram-alcohol reaction (manifested by flushing of the face)
  • Throbbing in the head and neck
  • Pulsating headache
  • Respiratorydifficulties
  • Nausea
  • Copious vomiting
  • Sweating
  • Thirst
  • Chest pain
  • Tachycardia
  • Palpitations
  • Marked hypotension
  • Giddiness
  • Weakness
  • Blurred vision
  • Confusion, and in severe cases
  • Respiratorydepression
  • Cardiovascularcollapse
  • Cardiac arrhythmias
  • Heart attack
  • Acute heart failure
  • Unconsciousness
  • Convulsions, and sudden death)
  • Rarely, blood dyscrasias

Potentially Fatal:

  • Severe hepatitis and hepatic failure

Warnings

Do not use Disulfiram in people with the following conditions:

  • Allergic reactions to this medicine or any of its contents, and thiuram compounds such as those used rubber vulcanization and pesticides.
  • Heart failure
  • Blocked arteries in the heart
  • High blood pressure
  • Liver disease
  • History of stroke
  • Mental illness, e.g., severe personality disorder, thoughts of self-harm

Inform your doctor and pharmacist if you are taking or using any of these medicines:

  • Alcohol containing preparations
  • Aspirin
  • Warfarin
  • Amitriptyline
  • Chlorpromazine
  • Chlordiazepoxide
  • Diazepam
  • Phenytoin
  • Isoniazid
  • Rifampicin
  • Clarithromycin
  • Metronidazole

Inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and non-prescription medicines.

This list does not include all medicines that may interact with Disulfiram.

How Does It Work?

Disulfiram is an aldehyde dehydrogenase inhibitor, the oxidative enzyme of acetaldehyde, a metabolite of alcohol accumulated in the blood, thereby producing unpleasant symptoms of disulfiram-alcohol reaction when a patient has taken small amounts of alcohol.

Uses 

Disulfiram is used  to treat the following conditions:

  • Adjunct in chronic alcoholism

Special Precautions and Connected Warnings

Take special precautions if you have the following conditions:

  • Diabetes mellitus
  • Epilepsy
  • Respiratorydisorders
  • Cerebral damage
  • Hypothyroidism
  • Abnormal EEG results
  • Multiple drug dependence
  • Renal and hepatic impairment
  • Pregnancy and lactation
  • Avoid alcohol, avoid vinegar, cider, axtracts and other food containing alcohol

Storage Conditions

  • Store at room temperature, away from excess heat and moisture
  • Store in a cool, dry place away from the reach of children.
  • Do not use Disulfiram that is expired or out of date.

Additional information

Dosage Type

Strength

Packaging Type

Number of Pills Per Order

10

Brand

Healing Pharma