Topiramate (Topaheal 50) 50 mg tablet is an anti-epileptic drug used on its own or with other medicines to treat epilepsy and prevent migraine headaches.
Drug = Topiramate
Number of Pills Per Order = 10
Strength = 50 mg
Manufacturer = Healing Pharma
How To Take Topiramate (Topaheal 50) 50 mg tablet
This medicine may be taken with or without food. Try to take it at the same time each day.
Swallow it whole. Do not chew or break the tablet.
Topiramate must be taken regularly for it to be effective. Continue taking Topiramate even when you feel better. Topiramate is not a cure, and you may need to take it long-term to keep your seizures under control. Do not stop taking Topiramate unless instructed otherwise as stopping it suddenly may worsen your condition.
Take Topiramate precisely as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Dosage of Topiramate (Topaheal 50) 50 mg
Adult: Epilepsy: Initial: 25 mg at night for one week, increased in increments of 25 or 50 mg at 1-2 weeks interval. Doses >25 mg should be taken in 2 divided doses. Maximum dose of 500 mg/day.
Adjunct for seizures associated w/ the Lennox-gastaut syndrome; Adjunct in epilepsy: Initial: 25-50 mg at night for one week, increased in increments of 25 or 50 mg at 1-2 weeks interval. Doses >25 mg should be taken in 2 divided doses.
Prophylaxis of migraine: Initial: 25 mg at night for one week. It increased in increments of 25 mg at weekly intervals. The usual dose is 50-100 mg/day in 2 divided doses. Maximum dose of 200 mg/day.
Missed Dose
If you miss a dose, skip the missed dose and return to your usual dosing schedule. If you often forget to take your medicine, let your doctor and pharmacist know.
Do not double a dose under any circumstances.
Overdose
Signs of overdose may include the following:
- Drowsiness
- Speech disturbances
- Convulsions
- Blurred vision
- Diplopia
- Impaired mental status
- Lethargy
- Abnormal coordination
- Hypotension
- Abdominal pain
- Stupor
- Agitation
- Dizziness
- Depression
Seek medical help immediately.
Contraindications
There is no data about the contraindications of Topiramate.
Side Effects
Topiramate may have the following side effects:
- Confusion
- Ataxia
- Impaired concentration and speech
- Fatigue
- Depression
- Dizziness
- Paraesthesia or hypoaesthesia
- Drowsiness
- Memory or cognition difficulty
- Anxiety
- Agitation
- Nervousness
- Emotional lability
- Mood disorders
- Anorexia
- Abdominal pain
- Asthenia
- Diplopia
- Leucopenia
- Nausea
- Diarrhea
- Nystagmus
- Insomnia
- Psychomotor retardation
- Nasopharyngitis
- Altered taste
- Visual disturbances
- Weight loss
- Increased risk of renal calculi
- Reduced sweating w/ hyperthermia
- Rarely, acute myopia w/ secondary angle-closure glaucoma.
Warnings
Inform your doctor and pharmacist if you are taking any of these medicines:
- Acetazolamide
- Dichlorphenamide
- Amitriptyline
- Diazepam
- Lithium
- Carbamazepine
- Phenytoin
- Phenobarbitone
- Valproic acid
- Digoxin
- Glyburide
- Birth control pills or hormone replacement therapy (HRT)
Inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and non-prescription medicines.
This list does not include all medicines that may interact with Topiramate.
How Does Topiramate (Topaheal 50) 50 mgWork?
Topiramate is a sulfamate-substituted monosaccharide that has no known precise mechanism of action. It may be due to voltage-dependent sodium channels blockade, augmentation of gamma-aminobutyric acid (GABA) at GABA A receptors activity, or inhibition of carbonic anhydrase and AMPA/kainate glutamate receptors.
Uses
Topiramate is used to treat the following conditions:
- Epilepsy
- Prophylaxis of migraine
- Adjunct for seizures associated with the Lennox-gastaut syndrome, Adjunct in epilepsy
Special Precautions and Connected Warnings
Take special precautions if you have the following conditions:
- Patient w/ predisposition to nephrolithiasis
- Conditions or medications that may increase the risk of metabolic acidosis
- Renal and hepatic impairment
- Children
- Pregnancy and lactation
- Avoid alcohol
Storage Conditions
- Store below 25°C. Protect from moisture.
- Store in a cool, dry place away from the reach of children.
- Do not use Topiramate that is expired or out of date.
