| Composition | Valacyclovir |
| Form | Tablet |
| Packaging Size | 10 Tablets pack |
| Usage/Application | Treatment of herpes |
| Brand Name | Valclovir |
| Dosage | 500mg |
Valacyclovir (Valclovir 500) 500 mg tablet is an antiviral drug used to treat and manage viral infections. It is used to treat herpes infections, cold sores, or infections of the skin or genitals. It may also be used after an organ transplant to prevent an infection with cytomegalovirus (CMV).
Drug =Valacyclovir
Number of Pills Per Order = 10
Strength = 500 mg
Manufacturer = Healing Pharma
How To Take Valacyclovir (Valclovir 500) 500 mg
This medicine may be taken with or without food. Try to take it at the same time each day. If you experience any stomach discomfort, you may take this medicine with food.
Valaciclovir must be taken at regular intervals for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
Do not skip any doses. You must complete the entire course of medicine. If you don’t, the infection will not be appropriately controlled.
Take this medicine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Dosage
Adult: Herpes zoster (shingles); Herpes zoster ophthalmicus: Immunocompetent patients: 1,000 mg three times a day for seven days. Immunocompromised patients: 1,000 mg three times a day for at least seven days and two days after crusting of lesions.
Herpes simplex infections of the skin and mucous membranes; Genital herpes: Immunocompetent patients: 500 mg twice a day for 3-5 days for recurrent episodes or up to 10 days for initial episodes. Immunocompromised patients: 1,000 mg twice a day for at least five days for recurrent episodes or up to 10 days for initial episodes. Treatment duration is based on the severity of the clinical condition and the patient’s immunological status.
Herpes labialis: 2,000 mg 12 hourly for one day.
Suppression of recurrent herpes simplex: Immunocompetent patients: 500 mg once daily. Patient with ≥ten relapses a year: 250 mg twice a day. Immunocompromised patients: 500 mg twice a day. Re-evaluate treatment after 6-12 months of therapy.
Prophylaxis of cytomegaloviral infections in immunocompromised patients; Patient following solid organ transplantation: 2,000 mg 4 times daily, usually for 90 days according to patient response.
Missed Dose
If you miss a dose, skip the missed dose and return to your usual dosing schedule. If you often forget to take your medicine, let your doctor and pharmacist know.
Do not double a dose under any circumstances.
Overdose of Valacyclovir (Valclovir 500) 500 mg
Signs of overdose may include the following:
- Acute renal failure
- Nausea
- Vomiting
- Confusion
- Agitation
- Hallucinations
- Decreased consciousness and coma
Seek medical help immediately.
Contraindications
People with the following medical conditions should not take Valacyclovir:
- Hypersensitivity
Side Effects
Valacyclovir may have the following side effects:
- Acute renal failure
- Central nervous system effects (e.g., agitation, hallucination, confusion, delirium, seizures, encephalopathy)
- Thrombocytopenia
- Leucopenia
- Nausea
- Abdominal pain
- Vomiting
- Diarrhea
- Fatigue
- Ataxia
- Fever
- Urticaria
- Rarely, anaphylaxis and angioedema
- Elevated liver enzymes.
- Dehydration
- Arthralgia
- Headache
- Dizziness
- Decreased consciousness
- Tremor
- Dysarthria
- Renal pain
- Haematuria
- Dysmenorrhea
- Nasopharyngitis
- Dyspnea
- Rashes
- Pruritus
- Photosensitivity
Potentially Fatal:
- Patients with advanced HIV infection receive high doses (8,000 mg daily) for a prolonged period: Thrombotic thrombocytopenic purpura, hemolytic uremic syndrome.
Warnings
Inform your doctor and pharmacist if you are taking any of these medicines:
- Tenofovir
- Foscarnet
- Cimetidine
- Probenecid
- Methotrexate
- Ciclosporin
- Tacrolimus
Inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and non-prescription medicines.
This list does not include all medicines that may interact with Valacyclovir.
How Does Valacyclovir (Valclovir 500) 500 mg Work?
Inform your doctor and pharmacist if you are taking any of these medicines:
- Tenofovir
- Foscarnet
- Cimetidine
- Probenecid
- Methotrexate
- Ciclosporin
- Tacrolimus
Inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and non-prescription medicines.
This list does not include all medicines that may interact with Valacyclovir.
Uses
Valacyclovir is used to treat the following conditions:
- Herpes zoster (shingles); Herpes zoster ophthalmicus
- Herpes simplex infections of the skin and mucous membranes; Genital herpes
- Herpes labialis
- Suppression of recurrent herpes simplex
- Prophylaxis of cytomegaloviral infections in immunocompromised patients
Special Precautions and Connected Warnings
Take special precautions if you have the following conditions:
- Patients inadequately hydrated or at risk of dehydration
- Immunocompromised patients
- Concomitant use with nephrotoxic agents
- Renal and hepatic impairment
- Elderly
- Pregnancy and lactation
- Avoid alcohol
Storage Conditions
- Store between 15-25°C.
- Store in a cool, dry place away from the reach of children.
- Do not use Valacyclovir that is expired or out of date.
