|Manufacturer||Healing Pharma India Pvt Ltd|
|Prescription/Non prescription||Non prescription|
|Deals in||Third Party Manufacturing|
Gabapentin (Gabatop-400) 400 mg capsule is a structural analog of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that is used to treat neuropathic pain, epilepsy and other types of pain.
Number of Pills Per Order = 10
Strength = 400 mg
Manufacturer = Healing Pharma
How To Take
This medicine may be taken with or without food. Try to make it at the same time each day.
Swallow it whole with a glass of water. If necessary, you may divide the standard tablet into two equal half-tablets along the break line. Half-tablets should be taken soon after splitting the pill.
This medicine must be taken regularly for it to be effective. Continue to make it even when you feel better. Do not stop taking Gabapentin unless instructed otherwise, as stopping it suddenly may worsen your condition. Your doctor will gradually reduce the dose before stopping it or changing it to another medicine.
Take Gabapentin precisely as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Dosage of Gabapentin (Gabatop-400) 400 mg
Adult: Epilepsy Initial: 300 mg once daily on the 1st day, 300 mg twice a day on the 2nd day, and 300 mg three times a day on the 3rd day. Alternatively, 300 mg three times a day on the 1st day. Doses may be further increased in 300 mg/day increments every 2-3 days according to individual response and tolerability. The effective dosing range is 900-3,600 mg daily. The total daily dose must be given in 3 equally divided doses, at maximum dose interval not exceeding 12 hours.
Neuropathic pain: Initial: 300 mg once daily on the 1st day, 300 mg twice a day on the 2nd day, and 300 mg three times a day on the 3rd day. Alternatively, 900 mg daily in 3 equally divided doses as the starting dose. Doses may be further increased in 300 mg/day increments every 2-3 days according to individual response and tolerability. Maximum of 3,600 mg/day.
Restless leg syndrome: As gabapentin enacarbil: modified-release preparation: Moderate to severe: 600 mg once daily at approximately 5 pm.
Postherpetic neuralgia: As gabapentin enacarbil: modified-release preparation: Initial: 600 mg once daily in the morning for three days, then increased to 600 mg twice a day.
If you miss a dose, skip the missed dose and return to your usual dosing schedule. If you often forget to take your medicine, let your doctor and pharmacist know.
Do not double a dose under any circumstances.
Overdose of Gabapentin (Gabatop-400) 400 mg
Signs of overdose may include the following:
- Double vision
- Slurred speech
- Mild diarrhea
- Loss of consciousness
Seek medical help immediately.
People with the following medical conditions should not take Gabapentin.
- Suicidal thoughts
- Myasthenia gravis
- A skeletal muscle disorder
- Decreased lung function
- Chronic obstructive pulmonary disease
- Chronic kidney disease stage 3-5
- Kidney disease with a likely reduction in kidney function
Gabapentin may have the following side effects:
- Suicidal ideation and behavior
- Neuropsychiatric effects in children (e.g., emotional lability, hostility, changes in behavior and thinking, hyperkinesia)
- Acute pancreatitis
- Respiratory depression
- Dry mouth
- Dental abnormality
- Peripheral edema
- Abnormal gait
- Viral infection
- Otitis media
- Accidental injury fracture
- Weight gain
- Decreased WBC
- Increased appetite
- Back pain
- Multiorgan hypersensitivity such as drug reaction with eosinophilia and systemic symptoms (DRESS).
Inform your doctor and pharmacist if you are taking or using any of these medicines:
Inform your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and non-prescription medicines.
This list does not include all medicines that may interact with Gabapentin.
How Does Gabapentin (Gabatop-400) 400 mg Work?
Gabapentin is structurally related to neurotransmitter GABA but does not bind to GABA A or B receptors nor influences the GABA uptake or synthesis. Instead, it binds with a high affinity to the α-2-δ-1 subunit of voltage-gated calcium channels, thereby modulates the release of excitatory neurotransmitters that participate in epileptogenesis and nociception.
Gabapentin is used to treat the following conditions:
- Neuropathic pain
- Restless leg syndrome
- Postherpetic neuralgia
Special Precautions and Connected Warnings
Take special precautions if you have the following conditions:
- Patients with mixed seizures including absences
- Compromised respiratory function
- Respiratory or neurological disease
- History of substance abuse (e.g., alcohol, benzodiazepines, cannabis, cocaine, opioids)
- Concomitant use with opioids
- Avoid abrupt withdrawal
- Renal impairment
- Children and the elderly
- Pregnancy and lactation
- Avoid alcohol
- Store below 25°C. Store it in a cool, dry place away from the children’s reach.
- Do not use Gabapentin that is expired or out of date.